{"id":3280,"date":"2026-01-14T18:04:38","date_gmt":"2026-01-14T09:04:38","guid":{"rendered":"https:\/\/blog.id774.net\/entry\/?p=3280"},"modified":"2026-03-26T23:37:17","modified_gmt":"2026-03-26T14:37:17","slug":"%e4%ba%ba%e9%96%93%e3%81%ae%e5%af%bf%e5%91%bd%e3%81%af%e3%81%a9%e3%81%93%e3%81%be%e3%81%a7%e4%bc%b8%e3%81%b3%e3%82%8b%e3%81%ae%e3%81%8b","status":"publish","type":"post","link":"https:\/\/blog.id774.net\/entry\/2026\/01\/14\/3280\/","title":{"rendered":"\u4eba\u9593\u306e\u5bff\u547d\u306f\u3069\u3053\u307e\u3067\u4f38\u3073\u308b\u306e\u304b"},"content":{"rendered":"

\u65e5\u672c\u7d4c\u6e08\u65b0\u805e<\/a>\u306b 2100 \u5e74\u306e\u5bff\u547d\u304c\u73fe\u5728\u3088\u308a\u4f38\u3073\u308b\u3053\u3068\u3092\u524d\u63d0\u3068\u3057\u305f\u8a18\u4e8b\u304c\u63b2\u8f09<\/a>\u3055\u308c\u3066\u3044\u305f\u3002\u305d\u3053\u3067\u672c\u7a3f\u3067\u306f\u30012100 \u5e74\u306b\u4eba\u9593\u306e\u5bff\u547d\u304c\u3069\u3053\u307e\u3067\u5230\u9054\u3057\u3046\u308b\u306e\u304b\u3092\u3001\u5e73\u5747\u5bff\u547d\u3001\u5065\u5eb7\u5bff\u547d<\/a>\u3001\u6700\u5927\u5bff\u547d\u3068\u3044\u3046 3 \u3064\u306e\u6307\u6a19\u3092\u53b3\u5bc6\u306b\u533a\u5225\u3057\u306a\u304c\u3089\u3001\u65e5\u672c\u306e\u73fe\u72b6\u3068\u5c06\u6765\u3092\u4e2d\u5fc3\u306b\u3001\u4eba\u53e3\u5b66<\/a>\uff08\u6b7b\u4ea1\u7387\u66f2\u7dda\u3068\u5206\u5e03\uff09\u3001\u516c\u8846\u885b\u751f<\/a>\uff08\u4fee\u6b63\u53ef\u80fd\u306a\u30ea\u30b9\u30af\u56e0\u5b50\u3068\u4ecb\u5165\uff09\u3001\u8001\u5316\u751f\u7269\u5b66<\/a>\uff08\u8001\u5316\u6a5f\u69cb\u3068\u9650\u754c\uff09\u3001\u5236\u5ea6\u8a2d\u8a08<\/a>\uff08\u533b\u7642\u3001\u5e74\u91d1\u3001\u52b4\u50cd\u3001\u502b\u7406\uff09\u3092\u63a5\u7d9a\u3057\u3066\u6574\u7406\u3059\u308b\u3002\u3053\u3053\u3067\u3044\u3046\u4e88\u60f3\u306f\u5360\u3044\u3067\u306f\u306a\u3044\u3002\u3044\u307e\u89b3\u6e2c\u3067\u304d\u308b\u7d71\u8a08\u3068\u3001\u5b66\u8853\u7814\u7a76\u304c\u793a\u3059\u30e1\u30ab\u30cb\u30ba\u30e0\u304b\u3089\u3001\u3069\u306e\u90e8\u5206\u304c\u4f38\u3073\u3084\u3059\u304f\u3001\u3069\u306e\u90e8\u5206\u304c\u4f38\u3073\u306b\u304f\u3044\u304b\u3092\u5206\u89e3\u3057\u3001\u8aad\u307f\u624b\u304c\u4e00\u304b\u3089\u7406\u89e3\u3057\u5224\u65ad\u3067\u304d\u308b\u5f62\u3067\u63d0\u793a\u3059\u308b\u3002<\/p>\n

\u7d50\u8ad6\u306e\u9aa8\u5b50\u3092\u5148\u306b\u7f6e\u304f\u3002\u7b2c\u4e00\u306b\u3001\u5e73\u5747\u5bff\u547d\u306f 2100 \u5e74\u306b\u5411\u3051\u3066\u4e0a\u304c\u308a\u5f97\u308b\u304c\u3001\u65e2\u306b\u4f4e\u6b7b\u4ea1\u7387\u793e\u4f1a\u3067\u3042\u308b\u65e5\u672c\u3067\u306f\u4f38\u3073\u65b9\u304c\u9013\u6e1b\u3057\u3084\u3059\u304f\u3001\u73fe\u5b9f\u7684\u30ec\u30f3\u30b8\u306f 90 \u301c 100 \u6b73\u4ed8\u8fd1\u306b\u306a\u308a\u3084\u3059\u3044\u3002\u7b2c\u4e8c\u306b\u3001\u5065\u5eb7\u5bff\u547d\u306f\u6700\u5927\u5bff\u547d\u3088\u308a\u73fe\u5b9f\u7684\u306b\u4f38\u3070\u3057\u3084\u3059\u304f\u3001\u30d5\u30ec\u30a4\u30eb\u9023\u9396\u3068\u8a8d\u77e5\u75c7\u306e\u4e00\u6b21\u4e88\u9632\u3092\u793e\u4f1a\u3068\u3057\u3066\u3069\u3053\u307e\u3067\u6a19\u6e96\u5316\u3067\u304d\u308b\u304b\u306b\u3088\u3063\u3066 80 \u4ee3\u5f8c\u534a\u304b\u3089 90 \u6b73\u8fd1\u508d\u307e\u3067\u5230\u9054\u3057\u3046\u308b\u3002\u7b2c\u4e09\u306b\u3001\u6700\u5927\u5bff\u547d\u306f\u5065\u5eb7\u5bff\u547d\u304c\u4f38\u3073\u308b\u307b\u3069\u8a18\u9332\u66f4\u65b0\u304c\u8d77\u304d\u3084\u3059\u304f\u306a\u308b\u4e00\u65b9\u3001110 \u6b73\u4ee5\u964d\u306e\u5c3e\u90e8\u306e\u6b7b\u4ea1\u7387\u66f2\u7dda\u305d\u306e\u3082\u306e\u3092\u62bc\u3057\u4e0b\u3052\u306a\u3044\u9650\u308a\u3001\u81ea\u7136\u306b 10 \u5e74\u5358\u4f4d\u3067\u4e0a\u65b9\u30b7\u30d5\u30c8\u3059\u308b\u72b6\u6cc1\u306f\u4f5c\u308a\u306b\u304f\u3044\u3002\u7b2c\u56db\u306b\u3001\u5065\u5eb7\u5bff\u547d 90 \u6b73\u793e\u4f1a\u306f\u6210\u7acb\u3057\u3046\u308b\u304c\u3001\u533b\u7642\u3001\u5e74\u91d1\u3001\u52b4\u50cd\u3001\u502b\u7406\u3092\u500b\u5225\u6700\u9069\u306e\u307e\u307e\u653e\u7f6e\u3059\u308b\u3068\u7834\u7dbb\u3057\u3084\u3059\u304f\u3001\u5236\u5ea6\u306e\u540c\u6642\u518d\u8a2d\u8a08\u304c\u5fc5\u8981\u306b\u306a\u308b\u3002<\/p>\n

\n

1. \u5bff\u547d\u3068\u3044\u3046\u8a00\u8449\u3092\u5206\u89e3\u3059\u308b\uff1a\u5e73\u5747\u5bff\u547d\u30fb\u5065\u5eb7\u5bff\u547d\u30fb\u6700\u5927\u5bff\u547d<\/h2>\n

\u5bff\u547d\u306e\u8b70\u8ad6\u304c\u6df7\u4e71\u3059\u308b\u6700\u5927\u306e\u7406\u7531\u306f\u3001\u7570\u306a\u308b\u91cf\u3092\u540c\u3058\u8a00\u8449\u3067\u547c\u3093\u3067\u3057\u307e\u3046\u70b9\u306b\u3042\u308b\u3002\u5e73\u5747\u5bff\u547d\u306f\u751f\u547d\u8868\u304b\u3089\u7b97\u51fa\u3055\u308c\u308b 0 \u6b73\u5e73\u5747\u4f59\u547d\u3067\u3042\u308a\u3001\u7279\u5b9a\u306e\u5e74\u9f62\u5e2f\u3067\u6b7b\u4ea1\u7387\u304c\u4e0b\u304c\u308c\u3070\u5e73\u5747\u5024\u3068\u3057\u3066\u53cd\u6620\u3055\u308c\u308b\u3002\u751f\u547d\u8868\u306e\u8003\u3048\u65b9\u81ea\u4f53\u306f\u4e16\u754c\u5171\u901a\u3067\u3042\u308a\u3001\u305f\u3068\u3048\u3070\u516c\u7684\u6a5f\u95a2\u306e\u65b9\u6cd5\u89e3\u8aac\u3068\u3057\u3066 NCHS \u3084\u5404\u56fd\u7d71\u8a08\u5c40\u306e\u8aac\u660e\u304c\u53c2\u7167\u3067\u304d\u308b[1]<\/a>\u3002\u5065\u5eb7\u5bff\u547d\u306f\u65e5\u672c\u306e\u653f\u7b56\u6307\u6a19\u3068\u3057\u3066\u300c\u5065\u5eb7\u4e0a\u306e\u554f\u984c\u3067\u65e5\u5e38\u751f\u6d3b\u304c\u5236\u9650\u3055\u308c\u308b\u3053\u3068\u306a\u304f\u751f\u6d3b\u3067\u304d\u308b\u671f\u9593\u300d\u3068\u5b9a\u7fa9\u3055\u308c\u3001\u5e73\u5747\u5bff\u547d\u3068\u306e\u5dee\u304c\u4e0d\u5065\u5eb7\u671f\u9593\u3068\u3057\u3066\u6271\u308f\u308c\u308b[2]<\/a>\u3002\u6700\u5927\u5bff\u547d\u306f\u7d71\u8a08\u7684\u306b\u89b3\u6e2c\u3055\u308c\u308b\u6700\u9ad8\u9f62\u8a18\u9332\u3001\u3042\u308b\u3044\u306f\u751f\u7269\u5b66\u7684\u306b\u60f3\u5b9a\u3055\u308c\u308b\u4e0a\u9650\u3092\u6307\u3057\u3001\u5e73\u5747\u5bff\u547d\u3084\u5065\u5eb7\u5bff\u547d\u3068\u306f\u5225\u306e\u529b\u5b66\u3067\u52d5\u304f\u3002<\/p>\n

\u3053\u306e 3 \u3064\u3092\u533a\u5225\u3059\u308b\u3068\u3001\u540c\u3058\u300c\u5bff\u547d\u304c\u4f38\u3073\u308b\u300d\u3067\u3082\u610f\u5473\u304c\u5909\u308f\u308b\u3002\u5e73\u5747\u5bff\u547d\u306f 70 \u301c 90 \u6b73\u306e\u6b7b\u4ea1\u7387\u304c\u5c11\u3057\u6539\u5584\u3059\u308b\u3060\u3051\u3067\u3082\u4f38\u3073\u308b\u3002\u5065\u5eb7\u5bff\u547d\u306f 60 \u301c 80 \u4ee3\u3067\u8d77\u304d\u308b\u751f\u6d3b\u6a5f\u80fd\u4f4e\u4e0b\u3092\u9045\u3089\u305b\u308b\u3068\u4f38\u3073\u308b\u3002\u4e00\u65b9\u3001\u6700\u5927\u5bff\u547d\u306f 110 \u6b73\u4ee5\u964d\u306e\u5c3e\u90e8\u3092\u62bc\u3057\u4e0b\u3052\u306a\u3044\u9650\u308a\u52d5\u304d\u306b\u304f\u3044\u3002\u3057\u305f\u304c\u3063\u3066 2100 \u5e74\u306e\u8b70\u8ad6\u3067\u306f\u3001\u3069\u306e\u6307\u6a19\u306e\u8a71\u3092\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u6bce\u56de\u660e\u793a\u3057\u306a\u3044\u3068\u3001\u8b70\u8ad6\u304c\u3059\u308c\u9055\u3046\u3002<\/p>\n

\n

2. \u65e5\u672c\u306e\u73fe\u5728\uff1a\u5065\u5eb7\u5bff\u547d\u30fb\u5e73\u5747\u5bff\u547d\u30fb\u4e0d\u5065\u5eb7\u671f\u9593<\/h2>\n

2.1 2022 \u5e74\u306e\u5065\u5eb7\u5bff\u547d\u3068\u5e73\u5747\u5bff\u547d<\/h3>\n

\u539a\u751f\u52b4\u50cd\u7701\u304c\u516c\u8868\u3057\u305f\u4ee4\u548c 4 \u5e74\u5024\u3067\u306f\u3001\u65e5\u672c\u306e\u5065\u5eb7\u5bff\u547d\u306f\u7537\u6027 72.57 \u5e74\u3001\u5973\u6027 75.45 \u5e74\u3067\u3042\u308b[3]<\/a>\u3002\u540c\u5e74\u306e\u5e73\u5747\u5bff\u547d\u306f e-\u30d8\u30eb\u30b9\u30cd\u30c3\u30c8\u306b\u3088\u308a\u7537\u6027 81.05 \u6b73\u3001\u5973\u6027 87.09 \u6b73\u3068\u793a\u3055\u308c\u3066\u3044\u308b[2]<\/a>\u3002\u3053\u3053\u3067\u91cd\u8981\u306a\u306e\u306f\u5358\u72ec\u306e\u6570\u5024\u3067\u306f\u306a\u304f\u3001\u5e73\u5747\u5bff\u547d\u3068\u5065\u5eb7\u5bff\u547d\u306e\u5dee\u3067\u3042\u308b\u30022022 \u5e74\u6642\u70b9\u3067\u5dee\u306f\u7537\u6027\u3067\u7d04 9 \u5e74\u3001\u5973\u6027\u3067\u7d04 12 \u5e74\u306b\u9054\u3057\u3001\u3053\u308c\u306f\u300c\u9577\u751f\u304d\u3067\u304d\u308b\u304c\u3001\u8981\u4ecb\u8b77\u3084\u751f\u6d3b\u5236\u9650\u306e\u671f\u9593\u3082\u9577\u3044\u300d\u3053\u3068\u3092\u610f\u5473\u3059\u308b[2]<\/a>\u3002<\/p>\n

2.2 \u4e0d\u5065\u5eb7\u671f\u9593\u304c\u610f\u5473\u3059\u308b\u3082\u306e\uff1a\u500b\u4eba\u306e\u751f\u6d3b\u3068\u793e\u4f1a\u306e\u30b3\u30b9\u30c8\u69cb\u9020<\/h3>\n

\u5e73\u5747\u5bff\u547d\u3068\u5065\u5eb7\u5bff\u547d\u306e\u5dee\u306f\u3001\u4eba\u751f\u306e\u7d42\u76e4\u306e\u8cea\u306e\u554f\u984c\u3067\u3042\u308b\u3068\u540c\u6642\u306b\u3001\u5236\u5ea6\u306e\u30b3\u30b9\u30c8\u69cb\u9020\u305d\u306e\u3082\u306e\u3067\u3042\u308b\u3002\u533b\u7642\u8cbb\u3001\u4ecb\u8b77\u8cbb\u3001\u5bb6\u65cf\u4ecb\u8b77\u3001\u5c31\u52b4\u7d99\u7d9a\u56f0\u96e3\u3001\u5730\u57df\u652f\u63f4\u9700\u8981\u304c\u3001\u3053\u306e\u5dee\u306e\u9577\u3055\u3068\u3057\u3066\u73fe\u308c\u308b\u3002\u5065\u5eb7\u5bff\u547d\u3092 1 \u5e74\u5ef6\u3070\u3059\u3053\u3068\u306f\u3001\u4eba\u53e3\u5168\u4f53\u3067\u898b\u308b\u3068\u300c\u91cd\u3044\u533b\u7642\u3084\u4ecb\u8b77\u3092\u5fc5\u8981\u3068\u3059\u308b\u671f\u9593\u300d\u3092 1 \u5e74\u5206\u5f8c\u308d\u3078\u305a\u3089\u3059\u3053\u3068\u306b\u8fd1\u304f\u3001\u5e73\u5747\u5bff\u547d\u3092 1 \u5e74\u5ef6\u3070\u3059\u3088\u308a\u5236\u5ea6\u306b\u52b9\u304f\u5834\u5408\u304c\u3042\u308b\u3002\u65e5\u672c\u3067\u4ecb\u8b77\u4fdd\u967a\u5236\u5ea6\u304c\u793e\u4f1a\u306e\u57fa\u76e4\u3068\u3057\u3066\u904b\u7528\u3055\u308c\u3066\u3044\u308b\u306e\u306f\u3001\u3053\u306e\u4e0d\u5065\u5eb7\u671f\u9593\u3092\u793e\u4f1a\u3067\u5438\u53ce\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u304b\u3089\u3067\u3042\u308b\u3002<\/p>\n

2.3 \u56fd\u969b\u6bd4\u8f03\u306e HALE\uff1a\u65e5\u672c\u306e\u50be\u5411\u3092\u3069\u3046\u8aad\u3080\u304b<\/h3>\n

\u56fd\u969b\u6bd4\u8f03\u3067\u306f WHO \u304c\u5065\u5eb7\u8abf\u6574\u5bff\u547d HALE \u3092\u63d0\u4f9b\u3057\u3066\u3044\u308b\u3002WHO \u306e\u56fd\u5225\u30da\u30fc\u30b8\u3067\u306f\u3001\u65e5\u672c\u306e HALE \u304c 2000 \u5e74\u306e 71.1 \u5e74\u304b\u3089 2021 \u5e74\u306e 73.4 \u5e74\u3078\u6539\u5584\u3057\u305f\u3068\u793a\u3055\u308c\u308b[4]<\/a>\u3002\u305f\u3060\u3057 HALE \u306f\u75be\u75c5\u8ca0\u8377\u63a8\u8a08\u306b\u57fa\u3065\u304f\u7d71\u8a08\u30e2\u30c7\u30eb\u3067\u3042\u308a\u3001\u65e5\u672c\u306e\u653f\u7b56\u6307\u6a19\u3068\u3057\u3066\u306e\u5065\u5eb7\u5bff\u547d\u3068\u306f\u7b97\u51fa\u6cd5\u304c\u7570\u306a\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u6570\u5024\u306e\u4e00\u81f4\u3092\u6c42\u3081\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u6539\u5584\u50be\u5411\u306e\u628a\u63e1\u306b\u4f7f\u3046\u306e\u304c\u9069\u5207\u3067\u3042\u308b\u3002WHO \u306e HALE \u30c0\u30c3\u30b7\u30e5\u30dc\u30fc\u30c9\u306f\u56fd\u969b\u6bd4\u8f03\u306e\u5165\u53e3\u3068\u3057\u3066\u6709\u7528\u3067\u3042\u308b[5]<\/a>\u3002<\/p>\n

\n

3. \u5bff\u547d\u304c\u4f38\u3073\u308b\u3068\u306f\u4f55\u304c\u8d77\u304d\u308b\u3053\u3068\u304b\uff1a\u6b7b\u4ea1\u7387\u66f2\u7dda\u30fb\u751f\u5b58\u66f2\u7dda\u30fb\u5c3e\u90e8<\/h2>\n

\u5bff\u547d\u306e\u5c06\u6765\u50cf\u3092\u5177\u4f53\u5316\u3059\u308b\u306b\u306f\u5e73\u5747\u5024\u3060\u3051\u3067\u306a\u304f\u5206\u5e03\u3068\u66f2\u7dda\u3092\u898b\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002\u4eba\u53e3\u5b66\u3067\u306f\u5e74\u9f62\u5225\u6b7b\u4ea1\u7387\uff08hazard\uff09\u3068\u751f\u5b58\u66f2\u7dda\uff08survival curve\uff09\u3092\u7528\u3044\u308b\u3002\u8fd1\u4ee3\u5316\u306b\u4f34\u3044\u751f\u5b58\u66f2\u7dda\u304c\u300c\u77e9\u5f62\u5316\u300d\u3057\u3001\u591a\u304f\u306e\u4eba\u304c\u9ad8\u9f62\u307e\u3067\u751f\u304d\u3001\u6700\u5f8c\u306b\u6025\u901f\u306b\u6b7b\u4ea1\u3059\u308b\u5f62\u3078\u8fd1\u3065\u304f\u3053\u3068\u304c\u89b3\u5bdf\u3055\u308c\u3066\u304d\u305f\u3002\u3053\u306e\u3068\u304d\u5e73\u5747\u5bff\u547d\u306f\u4e0a\u304c\u308b\u304c\u3001\u6700\u5927\u5bff\u547d\u306f\u751f\u5b58\u66f2\u7dda\u306e\u6700\u7d42\u5c3e\u90e8\u3067\u3042\u308a\u3001\u5c3e\u90e8\u306e\u6b7b\u4ea1\u7387\u304c\u9ad8\u3051\u308c\u3070\u5230\u9054\u8005\u306f\u6025\u6e1b\u8870\u3059\u308b\u3002\u56fd\u969b\u7684\u306a\u751f\u547d\u8868\u3068\u6b7b\u4ea1\u7387\u306e\u6574\u5099\u3068\u3057\u3066 Human Mortality Database \u306f\u4ee3\u8868\u7684\u306a\u57fa\u76e4\u3067\u3042\u308b[6]<\/a>\u3002<\/p>\n

\u307e\u305f\u3001\u6975\u9ad8\u9f62\u306e\u8b70\u8ad6\u3067\u306f\u30c7\u30fc\u30bf\u54c1\u8cea\u304c\u6838\u5fc3\u306b\u306a\u308b\u3002\u5e74\u9f62\u306e\u8aa4\u8a18\u3084\u767b\u9332\u306e\u6b20\u843d\u304c\u5c3e\u90e8\u3067\u4e0e\u3048\u308b\u5f71\u97ff\u306f\u5927\u304d\u304f\u3001\u691c\u8a3c\u6e08\u307f\u306e\u8d85\u9ad8\u9f62\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u304c\u91cd\u8981\u306b\u306a\u308b\u3002International Database on Longevity \u306f 105 \u6b73\u4ee5\u4e0a\u306e\u691c\u8a3c\u30c7\u30fc\u30bf\u3092\u63d0\u4f9b\u3057\u3001\u8d85\u9ad8\u9f62\u306e\u6b7b\u4ea1\u7387\u7814\u7a76\u306e\u57fa\u76e4\u306b\u306a\u3063\u3066\u3044\u308b[7]<\/a>\u3002\u500b\u5225\u8a18\u9332\u306e\u691c\u8a3c\u4f8b\u3068\u3057\u3066\u30b8\u30e3\u30f3\u30cc\u30fb\u30ab\u30eb\u30de\u30f3\u306e\u5e74\u9f62\u691c\u8a3c\u306f\u3088\u304f\u53c2\u7167\u3055\u308c\u308b[8]<\/a>\u3002<\/p>\n

\n

4. 2100 \u5e74\u306e\u5e73\u5747\u5bff\u547d\uff1a\u306a\u305c 90 \u301c 100 \u6b73\u304c\u73fe\u5b9f\u7684\u30ec\u30f3\u30b8\u306b\u306a\u308a\u3084\u3059\u3044\u304b<\/h2>\n

4.1 \u6b74\u53f2\u7684\u4e8b\u5b9f\uff1a\u6700\u9ad8\u6c34\u6e96\u56fd\u306e\u5e73\u5747\u5bff\u547d\u306f\u66f4\u65b0\u3055\u308c\u7d9a\u3051\u3066\u304d\u305f<\/h3>\n

\u5e73\u5747\u5bff\u547d\u306e\u9577\u671f\u4e0a\u6607\u3092\u793a\u3059\u53e4\u5178\u7684\u7d50\u679c\u3068\u3057\u3066\u3001Oeppen \u3068 Vaupel \u306f\u6700\u9ad8\u6c34\u6e96\u56fd\u306e\u5973\u6027\u5e73\u5747\u5bff\u547d\u304c\u9577\u671f\u306b\u308f\u305f\u308a\u307b\u307c\u76f4\u7dda\u7684\u306b\u4e0a\u6607\u3057\u3066\u304d\u305f\u3053\u3068\u3092\u793a\u3057\u3001\u300c\u9650\u754c\u3060\u3068\u601d\u308f\u308c\u305f\u6c34\u6e96\u304c\u66f4\u65b0\u3055\u308c\u7d9a\u3051\u3066\u304d\u305f\u300d\u3053\u3068\u3092\u8ad6\u3058\u305f[9]<\/a>\u3002\u3053\u306e\u77e5\u898b\u306f\u3001\u5e73\u5747\u5bff\u547d\u306b\u306f\u5358\u7d14\u306a\u5929\u4e95\u304c\u3042\u308b\u3068\u3044\u3046\u76f4\u611f\u304c\u6b74\u53f2\u7684\u306b\u306f\u5f53\u3066\u306b\u306a\u3089\u306a\u3044\u3053\u3068\u3092\u793a\u3059\u3002<\/p>\n

4.2 \u305f\u3060\u3057\u9013\u6e1b\u306f\u8d77\u304d\u308b\uff1a\u6b8b\u3055\u308c\u305f\u8ab2\u984c\u304c\u96e3\u3057\u3044\u9818\u57df\u306b\u79fb\u3063\u3066\u3044\u308b<\/h3>\n

\u3057\u304b\u3057\u3053\u306e\u4e8b\u5b9f\u306f\u30012100 \u5e74\u306b\u5e73\u5747\u5bff\u547d\u304c\u5fc5\u305a 110 \u6b73\u306b\u306a\u308b\u3053\u3068\u3092\u4fdd\u8a3c\u3057\u306a\u3044\u3002\u65e5\u672c\u306e\u3088\u3046\u306b\u65e2\u306b\u4f4e\u6b7b\u4ea1\u7387\u793e\u4f1a\u3067\u306f\u3001\u4e73\u5e7c\u5150\u6b7b\u4ea1\u3084\u611f\u67d3\u75c7\u6b7b\u4ea1\u306e\u5927\u5e45\u4f4e\u4e0b\u306e\u3088\u3046\u306a\u300c\u4f38\u3073\u3084\u3059\u3044\u4f59\u5730\u300d\u304c\u76f8\u5bfe\u7684\u306b\u5c0f\u3055\u3044\u3002\u4eca\u5f8c\u306e\u6539\u5584\u306f\u3001\u304c\u3093\u3084\u5faa\u74b0\u5668\u75be\u60a3\u306e\u4e00\u6b21\u4e88\u9632\u3001\u8907\u6570\u75be\u60a3\u4f75\u5b58\u306e\u7ba1\u7406\u3001\u611f\u67d3\u75c7\u306e\u518d\u6d41\u884c\u3001\u707d\u5bb3\u3084\u6c17\u5019\u8981\u56e0\u3001\u533b\u7642\u30a2\u30af\u30bb\u30b9\u683c\u5dee\u306a\u3069\u3001\u8907\u5408\u8981\u56e0\u3092\u6271\u3046\u5fc5\u8981\u304c\u3042\u308b\u3002\u3053\u308c\u3089\u306f\u5358\u4e00\u6280\u8853\u3067\u4e00\u6c17\u306b\u89e3\u6c7a\u3057\u306b\u304f\u304f\u3001\u3057\u305f\u304c\u3063\u3066\u5e73\u5747\u5bff\u547d\u306e\u4e0a\u6607\u306f\u7d9a\u3044\u3066\u3082\u901f\u5ea6\u306f\u9013\u6e1b\u3057\u3084\u3059\u3044\u3002<\/p>\n

4.3 \u73fe\u5b9f\u7684\u30ec\u30f3\u30b8\uff1a90 \u301c 100 \u6b73<\/h3>\n

\u4ee5\u4e0a\u3092\u8e0f\u307e\u3048\u3001\u672c\u7a3f\u306f 2100 \u5e74\u306e\u65e5\u672c\u306e\u5e73\u5747\u5bff\u547d\u304c 90 \u301c 100 \u6b73\u4ed8\u8fd1\u306b\u53ce\u675f\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u3044\u3046\u30ec\u30f3\u30b8\u3092\u63a1\u7528\u3059\u308b\u3002\u3053\u308c\u306f\u6700\u5927\u5bff\u547d\u306e\u4e0a\u9650\u7a81\u7834\u3092\u524d\u63d0\u3068\u3057\u306a\u3044\u3002\u5e73\u5747\u5bff\u547d\u3092 100 \u6b73\u8d85\u306b\u5927\u304d\u304f\u62bc\u3057\u4e0a\u3052\u308b\u306b\u306f\u3001\u8001\u5316\u305d\u306e\u3082\u306e\u3092\u5f37\u304f\u5236\u5fa1\u3059\u308b\u6280\u8853\u304c\u4eba\u53e3\u5168\u4f53\u306b\u666e\u53ca\u3057\u3001\u9577\u671f\u5b89\u5168\u6027\u304c\u78ba\u7acb\u3059\u308b\u3068\u3044\u3046\u5f37\u3044\u4eee\u5b9a\u304c\u5fc5\u8981\u306b\u306a\u308b\u3002<\/p>\n

\n

5. 2100 \u5e74\u306e\u5065\u5eb7\u5bff\u547d\uff1a\u3069\u3053\u307e\u3067\u4f38\u3070\u305b\u308b\u304b\uff08\u65e5\u672c\u306b\u6ce8\u76ee\uff09<\/h2>\n

5.1 \u5065\u5eb7\u5bff\u547d\u306f\u300c\u751f\u6d3b\u6a5f\u80fd\u306e\u9023\u9396\u300d\u3092\u9045\u3089\u305b\u308b\u554f\u984c\u3067\u3042\u308b<\/h3>\n

\u5065\u5eb7\u5bff\u547d\u306e\u7d42\u70b9\u306f\u300c\u6b7b\u300d\u3067\u306f\u306a\u304f\u300c\u65e5\u5e38\u751f\u6d3b\u304c\u5236\u9650\u3055\u308c\u308b\u72b6\u614b\u300d\u3078\u306e\u79fb\u884c\u3067\u3042\u308b\u3002\u305d\u306e\u4e3b\u8981\u306a\u51fa\u53e3\u304c\u30d5\u30ec\u30a4\u30eb\u3067\u3042\u308a\u3001\u30d5\u30ec\u30a4\u30eb\u306f\u7b4b\u529b\u4f4e\u4e0b\u3001\u4f53\u91cd\u6e1b\u5c11\u3001\u75b2\u52b4\u611f\u3001\u6b69\u884c\u901f\u5ea6\u4f4e\u4e0b\u306a\u3069\u304c\u91cd\u306a\u3063\u3066\u8ee2\u5012\u3001\u5165\u9662\u3001\u8981\u4ecb\u8b77\u3001\u6b7b\u4ea1\u30ea\u30b9\u30af\u3092\u62bc\u3057\u4e0a\u3052\u308b\u3002Fried \u3089\u306f\u30d5\u30ec\u30a4\u30eb\u3092\u81e8\u5e8a\u7684\u8868\u73fe\u578b\u3068\u3057\u3066\u5b9a\u7fa9\u3057\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u3068\u306e\u95a2\u9023\u3092\u793a\u3057\u305f[10]<\/a>\u3002\u4ee5\u5f8c\u306e\u30ec\u30d3\u30e5\u30fc\u3067\u3082\u30d5\u30ec\u30a4\u30eb\u304c\u591a\u9762\u7684\u6982\u5ff5\u3067\u3042\u308a\u3001\u4ecb\u5165\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u6574\u7406\u3055\u308c\u3066\u3044\u308b[11]<\/a>\u3002<\/p>\n

5.2 \u30d5\u30ec\u30a4\u30eb\u304c\u56fa\u5b9a\u5316\u3059\u308b\u5177\u4f53\u50cf\uff1a\u7b4b\u9aa8\u683c\u30fb\u4ee3\u8b1d\u30fb\u611f\u899a\u30fb\u793e\u4f1a\u53c2\u52a0\u304c\u9023\u9396\u3059\u308b<\/h3>\n

\u5065\u5eb7\u5bff\u547d\u304c\u77ed\u304f\u306a\u308b\u5178\u578b\u7d4c\u8def\u3092\u5177\u4f53\u7684\u306b\u63cf\u304f\u3002\u7b2c\u4e00\u306b\u7b4b\u9aa8\u683c\u30eb\u30fc\u30c8\u3067\u3042\u308b\u3002\u7b4b\u529b\u3068\u30d0\u30e9\u30f3\u30b9\u304c\u843d\u3061\u308b\u3068\u5916\u51fa\u304c\u6e1b\u308a\u3001\u6d3b\u52d5\u91cf\u4f4e\u4e0b\u304c\u7b4b\u529b\u4f4e\u4e0b\u3092\u3055\u3089\u306b\u9032\u3081\u3001\u8ee2\u5012\u30ea\u30b9\u30af\u3092\u4e0a\u3052\u308b\u3002\u8ee2\u5012\u304c\u9aa8\u6298\u306b\u3064\u306a\u304c\u308b\u3068\u3001\u5165\u9662\u3068\u5b89\u9759\u3067\u7b4b\u529b\u304c\u6025\u843d\u3057\u3001\u9000\u9662\u5f8c\u3082\u6d3b\u52d5\u304c\u623b\u3089\u305a\u3001\u8981\u4ecb\u8b77\u5316\u304c\u56fa\u5b9a\u5316\u3059\u308b\u3002\u8ee2\u5012\u305d\u306e\u3082\u306e\u304c\u4e16\u754c\u7684\u306a\u5065\u5eb7\u8ab2\u984c\u3067\u3042\u308a\u3001WHO \u306f\u8ee2\u5012\u304c\u6b7b\u4ea1\u3068\u969c\u5bb3\u306e\u4e3b\u8981\u56e0\u3067\u3042\u308b\u3053\u3068\u3092\u6574\u7406\u3057\u3066\u3044\u308b[12]<\/a>\u3002\u7b2c\u4e8c\u306b\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u3067\u3042\u308b\u3002\u9ad8\u9f62\u671f\u306e\u7b4b\u91cf\u3068\u7b4b\u529b\u4f4e\u4e0b\u306f\u30d5\u30ec\u30a4\u30eb\u3068\u91cd\u306a\u308a\u3001\u5b9a\u7fa9\u3068\u8a3a\u65ad\u306e\u6a19\u6e96\u5316\u3068\u3057\u3066\u6b27\u5dde\u30b3\u30f3\u30bb\u30f3\u30b5\u30b9 EWGSOP2 \u304c\u53c2\u7167\u3055\u308c\u308b[13]<\/a>\u3002\u7b2c\u4e09\u306b\u6804\u990a\u30eb\u30fc\u30c8\u3067\u3042\u308b\u3002\u9ad8\u9f62\u671f\u306f\u98df\u6b32\u4f4e\u4e0b\u3084\u5480\u56bc\u56a5\u4e0b\u6a5f\u80fd\u4f4e\u4e0b\u3067\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u304c\u4e0d\u8db3\u3057\u3084\u3059\u304f\u3001\u904b\u52d5\u3068\u6804\u990a\u306e\u7d44\u5408\u305b\u304c\u7b4b\u6a5f\u80fd\u7dad\u6301\u306b\u91cd\u8981\u3067\u3042\u308b[14]<\/a>\u3002\u7b2c\u56db\u306b\u611f\u899a\u3068\u793e\u4f1a\u53c2\u52a0\u30eb\u30fc\u30c8\u3067\u3042\u308b\u3002\u96e3\u8074\u3084\u8996\u529b\u4f4e\u4e0b\u306f\u4f1a\u8a71\u3092\u6e1b\u3089\u3057\u3001\u793e\u4f1a\u53c2\u52a0\u3092\u6e1b\u3089\u3057\u3001\u6291\u3046\u3064\u3084\u8a8d\u77e5\u8ca0\u8377\u4f4e\u4e0b\u3092\u62db\u304f\u3002\u96e3\u8074\u304c\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306b\u95a2\u9023\u3059\u308b\u3053\u3068\u306f\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u308b[15]<\/a>\u3002\u5b64\u7acb\u306f\u6b7b\u4ea1\u30ea\u30b9\u30af\u3068\u3082\u95a2\u9023\u3059\u308b\u305f\u3081\u3001\u5065\u5eb7\u5bff\u547d\u306e\u8a2d\u8a08\u306f\u533b\u7642\u3060\u3051\u3067\u306a\u304f\u793e\u4f1a\u53c2\u52a0\u306e\u8a2d\u8a08\u3092\u542b\u3080[16]<\/a>\u3002<\/p>\n

5.3 \u8a8d\u77e5\u75c7\u306f\u5065\u5eb7\u5bff\u547d 90 \u6b73\u306e\u6700\u5927\u306e\u5236\u7d04\u306b\u306a\u308a\u3084\u3059\u3044<\/h3>\n

\u5065\u5eb7\u5bff\u547d\u3092 80 \u4ee3\u5f8c\u534a\u304b\u3089 90 \u6b73\u8fd1\u508d\u3078\u8fd1\u3065\u3051\u308b\u5c40\u9762\u3067\u6700\u5927\u306e\u5236\u7d04\u306b\u306a\u308a\u3084\u3059\u3044\u306e\u304c\u8a8d\u77e5\u75c7\u3067\u3042\u308b\u3002\u7406\u7531\u306f\u5358\u7d14\u3067\u3001\u8a8d\u77e5\u75c7\u306f\u767a\u75c7\u5f8c\u306e\u53ef\u9006\u6027\u304c\u4f4e\u304f\u3001\u767a\u75c7\u3059\u308b\u3068\u65e5\u5e38\u751f\u6d3b\u5236\u9650\u304c\u6025\u901f\u306b\u5f37\u307e\u308b\u304b\u3089\u3067\u3042\u308b\u3002\u3055\u3089\u306b\u8a8d\u77e5\u75c7\u306f\u524d\u81e8\u5e8a\u671f\u304c\u9577\u304f\u300180 \u4ee3\u306e\u767a\u75c7\u3092\u6e1b\u3089\u3059\u306b\u306f\u4e2d\u5e74\u671f\u304b\u3089\u306e\u4e00\u6b21\u4e88\u9632\u304c\u5fc5\u8981\u306b\u306a\u308b\u3002Lancet Commission \u306e 2024 \u5e74\u5831\u544a\u306f\u3001\u6559\u80b2\u3001\u96e3\u8074\u3001\u55ab\u7159\u3001\u9ad8\u8840\u5727\u3001\u7cd6\u5c3f\u75c5\u3001\u80a5\u6e80\u3001\u8eab\u4f53\u6d3b\u52d5\u4e0d\u8db3\u3001\u793e\u4f1a\u7684\u5b64\u7acb\u306a\u3069 14 \u306e\u4fee\u6b63\u53ef\u80fd\u56e0\u5b50\u306b\u4ecb\u5165\u3059\u308b\u3053\u3068\u3067\u3001\u8a8d\u77e5\u75c7\u306e\u7d04 45 % \u304c\u4e88\u9632\u307e\u305f\u306f\u9045\u5ef6\u53ef\u80fd\u3068\u63a8\u8a08\u3057\u305f[17]<\/a>\u3002\u540c\u5831\u544a\u306e\u4f4d\u7f6e\u3065\u3051\u306f Commission portal \u3067\u3082\u6574\u7406\u3055\u308c\u3066\u3044\u308b[18]<\/a>\u3002WHO \u3082\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3068\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u4f4e\u6e1b\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u793a\u3057\u3001\u8eab\u4f53\u6d3b\u52d5\u3001\u98df\u4e8b\u3001\u7981\u7159\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u3001\u4f53\u91cd\u7ba1\u7406\u3001\u9ad8\u8840\u5727\u3084\u7cd6\u5c3f\u75c5\u306e\u7ba1\u7406\u306a\u3069\u3092\u63a8\u5968\u3057\u3066\u3044\u308b[19]<\/a>\u3002\u8a73\u7d30\u306f NCBI Bookshelf \u7248\u3067\u78ba\u8a8d\u3067\u304d\u308b[20]<\/a>\u3002<\/p>\n

5.4 \u591a\u9818\u57df\u4ecb\u5165\u306e\u5b9f\u4f8b\uff1aFINGER \u3068\u300c\u5065\u5eb7\u5bff\u547d\u300d\u578b\u306e\u8a66\u9a13\u8a2d\u8a08<\/h3>\n

\u8a8d\u77e5\u75c7\u4e88\u9632\u3084\u6a5f\u80fd\u7dad\u6301\u3067\u306f\u3001\u5358\u4e00\u4ecb\u5165\u3088\u308a\u591a\u9818\u57df\u4ecb\u5165\uff08\u904b\u52d5\u3001\u6804\u990a\u3001\u8a8d\u77e5\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3001\u8840\u7ba1\u30ea\u30b9\u30af\u7ba1\u7406\u306a\u3069\uff09\u306e\u8a66\u9a13\u304c\u91cd\u8981\u306b\u306a\u308b\u3002FINGER \u8a66\u9a13\u306f 2 \u5e74\u9593\u306e\u591a\u9818\u57df\u4ecb\u5165\u3067\u8a8d\u77e5\u6a5f\u80fd\u306e\u6539\u5584\u3092\u793a\u3057\u3001\u4e00\u6b21\u4e88\u9632\u3068\u751f\u6d3b\u4ecb\u5165\u304c\u73fe\u5b9f\u306e\u4ecb\u5165\u30d1\u30c3\u30b1\u30fc\u30b8\u3068\u3057\u3066\u6210\u7acb\u3057\u3046\u308b\u3053\u3068\u3092\u793a\u3057\u305f[21]<\/a>\u3002\u3053\u306e\u65b9\u5411\u6027\u306f\u300c\u5bff\u547d\u3092\u5ef6\u3070\u3059\u300d\u3088\u308a\u300c\u6a5f\u80fd\u3092\u4fdd\u3064\u300d\u8a55\u4fa1\u306b\u5411\u3044\u3066\u304a\u308a\u3001\u5065\u5eb7\u5bff\u547d\u306e\u8b70\u8ad6\u3068\u6574\u5408\u3059\u308b\u3002<\/p>\n

5.5 \u8840\u5727\u7ba1\u7406\u304c\u6a5f\u80fd\u306b\u6ce2\u53ca\u3059\u308b\u4f8b\uff1aSPRINT MIND<\/h3>\n

\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u7ba1\u7406\u304c\u5065\u5eb7\u5bff\u547d\uff08\u6a5f\u80fd\uff09\u306b\u52b9\u304f\u4f8b\u3068\u3057\u3066 SPRINT MIND \u304c\u91cd\u8981\u3067\u3042\u308b\u3002JAMA\uff082019\uff09\u3067\u306f\u3001\u53b3\u683c\u306a\u8840\u5727\u7ba1\u7406\u304c\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff08MCI\uff09\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u3001MCI \u307e\u305f\u306f\u8a8d\u77e5\u75c7\u306e\u8907\u5408\u30a2\u30a6\u30c8\u30ab\u30e0\u3082\u4f4e\u4e0b\u3055\u305b\u305f[22]<\/a>\u3002SPRINT \u672c\u4f53\u306f\u53b3\u683c\u964d\u5727\u304c\u4e3b\u8981\u5fc3\u8840\u7ba1\u30a2\u30a6\u30c8\u30ab\u30e0\u3092\u6539\u5584\u3057\u305f\u3053\u3068\u3092\u793a\u3057\u3066\u304a\u308a\u3001\u8840\u7ba1\u30ea\u30b9\u30af\u7ba1\u7406\u304c\u6b7b\u4ea1\u3068\u6a5f\u80fd\u306e\u53cc\u65b9\u306b\u5f71\u97ff\u3059\u308b\u53ef\u80fd\u6027\u3092\u793a\u3059[23]<\/a>\u3002<\/p>\n

5.6 \u5065\u5eb7\u5bff\u547d\u3092\u62bc\u3057\u4e0a\u3052\u308b\u5b9f\u88c5\u30ec\u30d0\u30fc\uff1a\u904b\u52d5\u30fb\u6804\u990a\u30fb\u8ee2\u5012\u4e88\u9632\u30fb\u793e\u4f1a\u53c2\u52a0<\/h3>\n

\u5065\u5eb7\u5bff\u547d\u3092\u62bc\u3057\u4e0a\u3052\u308b\u30ec\u30d0\u30fc\u306f\u3001\u533b\u7642\u306e\u9ad8\u5ea6\u5316\u3060\u3051\u3067\u306f\u306a\u3044\u3002\u65e5\u5e38\u306e\u884c\u52d5\u3068\u74b0\u5883\u8a2d\u8a08\u304c\u4e3b\u6226\u5834\u306b\u306a\u308b\u3002\u8eab\u4f53\u6d3b\u52d5\u306b\u3064\u3044\u3066\u306f WHO \u304c\u8eab\u4f53\u6d3b\u52d5\u3068\u5ea7\u4f4d\u884c\u52d5\u306b\u95a2\u3059\u308b\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u63d0\u793a\u3057\u3066\u304a\u308a\u3001\u9ad8\u9f62\u8005\u306b\u5bfe\u3057\u3066\u3082\u7b4b\u529b\u6d3b\u52d5\u3092\u542b\u3080\u63a8\u5968\u3092\u6574\u7406\u3057\u3066\u3044\u308b[24]<\/a>\u3002\u8ee2\u5012\u4e88\u9632\u3001\u6804\u990a\u3001\u904b\u52d5\u306f\u76f8\u4e92\u306b\u88dc\u5b8c\u3057\u5408\u3046\u3002\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u8a3a\u65ad\u306e\u6a19\u6e96\u5316\u306f\u4ecb\u5165\u306e\u5bfe\u8c61\u3092\u660e\u78ba\u306b\u3059\u308b[13]<\/a>\u3002\u4e00\u65b9\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u3088\u3046\u306a\u5358\u4e00\u624b\u6bb5\u306f\u4e07\u80fd\u3067\u306f\u306a\u304f\u3001\u305f\u3068\u3048\u3070\u30d3\u30bf\u30df\u30f3 D \u306e\u8ee2\u5012\u30fb\u9aa8\u6298\u4e88\u9632\u52b9\u679c\u306f\u7814\u7a76\u306b\u3088\u308a\u7d50\u679c\u304c\u63fa\u308c\u3066\u304a\u308a\u3001\u500b\u5225\u5316\u3068\u5168\u4f53\u8a2d\u8a08\u304c\u5fc5\u8981\u306b\u306a\u308b[25]<\/a>\u3002<\/p>\n

5.7 2100 \u5e74\u306e\u65e5\u672c\u306e\u5065\u5eb7\u5bff\u547d\u30ec\u30f3\u30b8\uff1a\u793e\u4f1a\u8a2d\u8a08\u3067\u5206\u5c90\u3059\u308b<\/h3>\n

\u4ee5\u4e0a\u3092\u8e0f\u307e\u3048\u308b\u3068\u30012100 \u5e74\u306e\u65e5\u672c\u306e\u5065\u5eb7\u5bff\u547d\u306f\u793e\u4f1a\u5b9f\u88c5\u306e\u9054\u6210\u5ea6\u306b\u3088\u3063\u3066\u30ec\u30f3\u30b8\u304c\u5206\u5c90\u3059\u308b\u3002\u4fdd\u5b88\u7684\u306b\u306f 78 \u301c 85 \u6b73\u7a0b\u5ea6\uff08\u7537\u5973\u5dee\u3042\u308a\uff09\u3067\u63a8\u79fb\u3057\u3046\u308b\u3002\u4e88\u9632\u304c\u6a19\u6e96\u5316\u3055\u308c\u3001\u30d5\u30ec\u30a4\u30eb\u5bfe\u7b56\u3068\u793e\u4f1a\u53c2\u52a0\u304c\u5730\u57df\u306b\u5b9a\u7740\u3057\u3001\u8a8d\u77e5\u75c7\u4e00\u6b21\u4e88\u9632\u304c\u4e2d\u5e74\u671f\u304b\u3089\u6a5f\u80fd\u3059\u308b\u5834\u5408\u300180 \u4ee3\u5f8c\u534a\u304b\u3089 90 \u6b73\u8fd1\u508d\u306b\u8fd1\u3065\u304f\u3002\u3053\u3053\u3067\u91cd\u8981\u306a\u306e\u306f\u3001\u3053\u308c\u306f\u751f\u7269\u5b66\u306e\u58c1\u3068\u3044\u3046\u3088\u308a\u3001\u5236\u5ea6\u3068\u884c\u52d5\u306e\u58c1\u3067\u3042\u308b\u3068\u3044\u3046\u70b9\u3067\u3042\u308b\u3002<\/p>\n

\n

6. \u6700\u5927\u5bff\u547d\u306f\u306a\u305c\u4f38\u3073\u306b\u304f\u3044\u304b\uff1a\u8001\u5316\u751f\u7269\u5b66\u3068\u4eba\u53e3\u5b66\u306e\u63a5\u7d9a<\/h2>\n

6.1 \u8001\u5316\u306f\u5358\u4e00\u539f\u56e0\u3067\u306f\u306a\u3044\uff1aHallmarks of Aging<\/h3>\n

\u6700\u5927\u5bff\u547d\u304c\u4f38\u3073\u306b\u304f\u3044\u7b2c\u4e00\u306e\u7406\u7531\u306f\u3001\u8001\u5316\u304c\u5358\u4e00\u539f\u56e0\u3067\u306f\u306a\u304f\u3001\u591a\u56e0\u5b50\u304c\u76f8\u4e92\u9023\u95a2\u3059\u308b\u73fe\u8c61\u3060\u304b\u3089\u3067\u3042\u308b\u3002L\u00f3pez-Ot\u00edn \u3089\u306f\u8001\u5316\u3092\u8907\u6570\u306e Hallmarks \u3068\u3057\u3066\u6574\u7406\u3057\u3001\u30b2\u30ce\u30e0\u4e0d\u5b89\u5b9a\u6027\u3001\u30c6\u30ed\u30e1\u30a2\u77ed\u7e2e\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u5909\u5316\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u6052\u5e38\u6027\u306e\u7834\u7dbb\u3001\u6804\u990a\u611f\u77e5\u306e\u7570\u5e38\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u4e0d\u5168\u3001\u7d30\u80de\u8001\u5316\u3001\u5e79\u7d30\u80de\u67af\u6e07\u3001\u7d30\u80de\u9593\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u5909\u5316\u306a\u3069\u3092\u5217\u6319\u3057\u3001\u76f8\u4e92\u9023\u95a2\u3092\u5f37\u8abf\u3057\u305f[26]<\/a>\u30022023 \u5e74\u306e\u30a2\u30c3\u30d7\u30c7\u30fc\u30c8\u3067\u306f\u6162\u6027\u708e\u75c7\u3084\u8178\u5185\u74b0\u5883\u5931\u8abf\u306a\u3069\u304c\u8ffd\u52a0\u3055\u308c\u3001\u5168\u8eab\u6027\u9023\u9396\u304c\u3088\u308a\u524d\u666f\u5316\u3057\u305f[27]<\/a>\u3002110 \u6b73\u4ee5\u964d\u3067\u306f\u300c\u304c\u3093\u3060\u3051\u3092\u6291\u3048\u308c\u3070\u3088\u3044\u300d\u300c\u5faa\u74b0\u5668\u3060\u3051\u3092\u6291\u3048\u308c\u3070\u3088\u3044\u300d\u3068\u3044\u3046\u72b6\u6cc1\u3067\u306f\u306a\u304f\u3001\u8907\u6570\u306e\u6545\u969c\u30e2\u30fc\u30c9\u304c\u540c\u6642\u306b\u9650\u754c\u5316\u3057\u3084\u3059\u3044\u3002<\/p>\n

6.2 \u708e\u75c7\u306e\u81ea\u5df1\u5897\u5e45\uff1ainflammaging \u3068\u514d\u75ab\u8001\u5316<\/h3>\n

\u8d85\u9ad8\u9f62\u57df\u3067\u652f\u914d\u7684\u306b\u306a\u308a\u3084\u3059\u3044\u57fa\u76e4\u8981\u56e0\u3068\u3057\u3066\u6162\u6027\u708e\u75c7\uff08inflammaging\uff09\u304c\u3042\u308b\u3002Franceschi \u3089\u306f inflammaging \u6982\u5ff5\u3092\u63d0\u793a\u3057\u3001\u52a0\u9f62\u306b\u4f34\u3046\u4f4e\u5ea6\u6162\u6027\u708e\u75c7\u304c\u591a\u75be\u60a3\u30ea\u30b9\u30af\u3092\u5e95\u4e0a\u3052\u3059\u308b\u53ef\u80fd\u6027\u3092\u8ad6\u3058\u305f[28]<\/a>\u3002\u305d\u306e\u5f8c\u306e\u30ec\u30d3\u30e5\u30fc\u3067\u3082\u3001\u514d\u75ab\u8001\u5316\u3001\u4ee3\u8b1d\u3001\u8178\u5185\u74b0\u5883\u306a\u3069\u591a\u69d8\u306a\u8981\u56e0\u304c\u708e\u75c7\u3092\u7dad\u6301\u3057\u3046\u308b\u3053\u3068\u304c\u6574\u7406\u3055\u308c\u3066\u3044\u308b[29]<\/a>\u3002\u5c3e\u90e8\u3067\u306f\u3001\u708e\u75c7\u304c\u539f\u56e0\u3067\u3082\u7d50\u679c\u3067\u3082\u3042\u308b\u60aa\u5faa\u74b0\u306b\u306a\u308a\u3084\u3059\u304f\u3001\u5358\u4e00\u81d3\u5668\u6cbb\u7642\u306e\u52b9\u679c\u304c\u8584\u308c\u3084\u3059\u3044\u3002<\/p>\n

6.3 \u5de5\u5b66\u7684\u76f4\u611f\uff1a\u4fe1\u983c\u6027\u7406\u8ad6\u3068\u300c\u4ea4\u63db\u4e0d\u80fd\u300d<\/h3>\n

\u8001\u5316\u3092\u5de5\u5b66\u7684\u306b\u6349\u3048\u308b\u76f4\u611f\u3068\u3057\u3066\u4fe1\u983c\u6027\u7406\u8ad6\u304c\u3042\u308b\u3002Gavrilov \u3068 Gavrilova \u306f\u3001\u751f\u4f53\u306e\u3088\u3046\u306b\u5197\u9577\u6027\u3092\u6301\u3064\u30b7\u30b9\u30c6\u30e0\u3067\u3082\u3001\u90e8\u54c1\u304c\u4ea4\u63db\u4e0d\u80fd\u3067\u3042\u308c\u3070\u6545\u969c\u30e2\u30fc\u30c9\u304c\u7d2f\u7a4d\u3057\u3001\u5e74\u9f62\u3068\u3068\u3082\u306b\u6545\u969c\u7387\u304c\u4e0a\u304c\u308a\u3046\u308b\u3053\u3068\u3092\u8ad6\u3058\u305f[30]<\/a>\u3002\u751f\u4f53\u306f\u5197\u9577\u6027\u304c\u5927\u304d\u3044\u304c\u3001\u5e79\u7d30\u80de\u3001\u514d\u75ab\u7cfb\u3001\u8840\u7ba1\u3001\u795e\u7d4c\u7cfb\u306a\u3069\u91cd\u8981\u90e8\u54c1\u306f\u5b8c\u5168\u306b\u306f\u4ea4\u63db\u3067\u304d\u306a\u3044\u3002\u82e5\u3044\u6642\u671f\u306f\u5197\u9577\u6027\u3067\u5438\u53ce\u3067\u304d\u3066\u3082\u3001\u8d85\u9ad8\u9f62\u3067\u306f\u6545\u969c\u306e\u7a4d\u307f\u91cd\u306d\u304c\u81e8\u754c\u3092\u8d85\u3048\u3084\u3059\u3044\u3002<\/p>\n

6.4 \u6975\u9ad8\u9f62\u306e\u6b7b\u4ea1\u7387\uff1a105 \u6b73\u4ee5\u964d\u306e\u30d7\u30e9\u30c8\u30fc\u3068\u3001\u305d\u306e\u610f\u5473<\/h3>\n

\u4eba\u53e3\u5b66\u7684\u306b\u306f\u3001105 \u6b73\u4ee5\u964d\u3067\u6b7b\u4ea1\u7387\u304c\u9ad8\u3044\u6c34\u6e96\u3067\u982d\u6253\u3061\u306b\u306a\u308b\uff08late-life mortality plateau\uff09\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308b\u3002Barbi \u3089\u306f\u30a4\u30bf\u30ea\u30a2\u306e\u691c\u8a3c\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3001105 \u6b73\u4ee5\u964d\u3067\u6b7b\u4ea1\u30cf\u30b6\u30fc\u30c9\u304c\u307b\u307c\u4e00\u5b9a\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u305f[31]<\/a>\u3002\u3053\u3053\u3067\u91cd\u8981\u306a\u306e\u306f\u3001\u982d\u6253\u3061\u3067\u3042\u3063\u3066\u3082\u6c34\u6e96\u304c\u9ad8\u3044\u3053\u3068\u3067\u3042\u308a\u3001\u5230\u9054\u8005\u304c\u5e74\u3054\u3068\u306b\u6025\u6e1b\u8870\u3059\u308b\u70b9\u3067\u3042\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u5065\u5eb7\u5bff\u547d\u306e\u5ef6\u4f38\u3067 110 \u6b73\u5230\u9054\u8005\u304c\u5897\u3048\u3066\u3082\u3001\u5c3e\u90e8\u306e\u6b7b\u4ea1\u7387\u66f2\u7dda\u304c\u305d\u306e\u307e\u307e\u306a\u3089 120 \u6b73\u53f0\u5f8c\u534a\u306e\u5230\u9054\u8005\u306f\u983b\u51fa\u3057\u306b\u304f\u3044\u3002<\/p>\n

6.5 \u4e0a\u9650\u8ad6\u4e89\uff1a\u4e0a\u9650\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u3088\u308a\u3001\u5c3e\u90e8\u304c\u786c\u3044\u3053\u3068\u304c\u672c\u8cea<\/h3>\n

\u6700\u5927\u5bff\u547d\u306b\u81ea\u7136\u306a\u4e0a\u9650\u304c\u3042\u308b\u53ef\u80fd\u6027\u3092\u4e3b\u5f35\u3059\u308b\u7814\u7a76\u3068\u3057\u3066 Dong \u3089\uff08Nature, 2016\uff09\u304c\u77e5\u3089\u308c\u3001\u8b70\u8ad6\u3092\u6d3b\u6027\u5316\u3055\u305b\u305f[32]<\/a>\u3002\u305f\u3060\u3057\u672c\u7a3f\u306e\u76ee\u7684\u306f\u4e0a\u9650\u306e\u6709\u7121\u3092\u88c1\u5b9a\u3059\u308b\u3053\u3068\u3067\u306f\u306a\u3044\u3002\u5b9f\u52d9\u7684\u306b\u91cd\u8981\u306a\u306e\u306f\u3001\u4e0a\u9650\u304c\u53b3\u5bc6\u306b\u5b58\u5728\u3059\u308b\u304b\u5426\u304b\u306b\u95a2\u308f\u3089\u305a\u3001\u5c3e\u90e8\u306e\u6b7b\u4ea1\u7387\u66f2\u7dda\u3092\u4e0b\u3052\u308b\u3053\u3068\u304c\u6975\u3081\u3066\u96e3\u3057\u3044\u3068\u3044\u3046\u70b9\u3067\u3042\u308b\u3002\u305d\u306e\u96e3\u3057\u3055\u306f\u3001\u8001\u5316\u304c\u591a\u56e0\u5b50\u3067\u3042\u308a\u3001\u5c3e\u90e8\u3067\u306f\u591a\u81d3\u5668\u304c\u540c\u6642\u306b\u9650\u754c\u5316\u3057\u3084\u3059\u3044\u3068\u3044\u3046\u69cb\u9020\u304b\u3089\u8aac\u660e\u3067\u304d\u308b\u3002<\/p>\n

\n

7. \u5c3e\u90e8\u306b\u8e0f\u307f\u8fbc\u3080\uff1a\u6700\u5927\u5bff\u547d\u3092\u62bc\u3057\u4e0a\u3052\u308b\u4ecb\u5165\u306f\u306a\u305c\u96e3\u3057\u3044\u304b<\/h2>\n

7.1 \u8001\u5316\u7d30\u80de\uff08senescence\uff09\u3068 SASP\uff1a\u5168\u8eab\u708e\u75c7\u3068\u7dda\u7dad\u5316\u306e\u30cf\u30d6<\/h3>\n

\u6700\u5927\u5bff\u547d\u57df\u3067\u306f\u8907\u6570\u7d4c\u8def\u306e\u540c\u6642\u6700\u9069\u5316\u304c\u5fc5\u8981\u306b\u306a\u308b\u3002\u8001\u5316\u7d30\u80de\u306e\u84c4\u7a4d\u306f SASP\uff08\u708e\u75c7\u6027\u5206\u6ccc\uff09\u3092\u901a\u3058\u3066\u6162\u6027\u708e\u75c7\u3084\u7dda\u7dad\u5316\u3092\u5897\u5e45\u3057\u3001\u5468\u8fba\u7d44\u7e54\u306e\u6a5f\u80fd\u4f4e\u4e0b\u3092\u4fc3\u3059\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u30de\u30a6\u30b9\u3067\u306f p16 \u967d\u6027\u7d30\u80de\u3092\u9664\u53bb\u3059\u308b\u3053\u3068\u3067\u52a0\u9f62\u95a2\u9023\u969c\u5bb3\u304c\u9045\u308c\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3001\u8001\u5316\u7d30\u80de\u304c\u5065\u5eb7\u5bff\u547d\u77ed\u7e2e\u306b\u56e0\u679c\u7684\u306b\u95a2\u4e0e\u3057\u3046\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f[33]<\/a>\u3002\u7d9a\u304f\u7814\u7a76\u3067\u3082 p16 \u967d\u6027\u7d30\u80de\u304c\u5065\u5eb7\u5bff\u547d\u3092\u77ed\u7e2e\u3057\u3046\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b[34]<\/a>\u3002\u305d\u306e\u5f8c\u3001\u8001\u5316\u7d30\u80de\u3092\u6a19\u7684\u3068\u3059\u308b senolytics \u306e\u6982\u5ff5\u3068\u8ab2\u984c\u304c\u6574\u7406\u3055\u308c\u3066\u3044\u308b[35]<\/a>\u3002\u305f\u3060\u3057\u4eba\u9593\u3067\u5c3e\u90e8\u306b\u52b9\u304b\u305b\u308b\u306b\u306f\u3001\u816b\u760d\u6291\u5236\u3084\u5275\u50b7\u6cbb\u7652\u3068\u306e\u30c8\u30ec\u30fc\u30c9\u30aa\u30d5\u3001\u81d3\u5668\u3054\u3068\u306e\u6700\u9069\u5316\u3001\u9577\u671f\u5b89\u5168\u6027\u3092\u540c\u6642\u306b\u6e80\u305f\u3059\u5fc5\u8981\u304c\u3042\u308a\u3001\u3053\u3053\u304c\u6700\u5927\u5bff\u547d\u5ef6\u4f38\u306e\u96e3\u3057\u3055\u3092\u8c61\u5fb4\u3059\u308b\u3002<\/p>\n

7.2 \u30af\u30ed\u30fc\u30f3\u6027\u9020\u8840\uff08CHIP\uff09\uff1a\u8840\u6db2\u304c\u4f5c\u308b\u5185\u56e0\u6027\u30ea\u30b9\u30af\u6e90<\/h3>\n

\u52a0\u9f62\u306b\u4f34\u3044\u9020\u8840\u5e79\u7d30\u80de\u306e\u5909\u7570\u30af\u30ed\u30fc\u30f3\u304c\u5897\u3048\u308b CHIP \u306f\u3001\u8840\u6db2\u304c\u3093\u3060\u3051\u3067\u306a\u304f\u3001\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u60a3\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002Jaiswal \u3089\uff08NEJM, 2017\uff09\u306f CHIP \u304c\u51a0\u52d5\u8108\u75be\u60a3\u30ea\u30b9\u30af\u5897\u52a0\u3068\u95a2\u9023\u3057\u3001\u708e\u75c7\u6a5f\u5e8f\u3092\u4ecb\u3057\u3066\u52d5\u8108\u786c\u5316\u3092\u4fc3\u9032\u3057\u3046\u308b\u3053\u3068\u3092\u793a\u3057\u305f[36]<\/a>\u3002\u5c3e\u90e8\u3067\u306f\u3001\u3053\u306e\u7a2e\u306e\u5185\u56e0\u6027\u30ea\u30b9\u30af\u6e90\u304c\u5168\u8eab\u306e\u57fa\u76e4\u30ea\u30b9\u30af\u3092\u5e95\u4e0a\u3052\u3057\u3001\u5358\u4e00\u81d3\u5668\u4ecb\u5165\u306e\u52b9\u679c\u3092\u76f8\u6bba\u3057\u3084\u3059\u304f\u3059\u308b\u3002<\/p>\n

7.3 geroscience\uff1a\u8a55\u4fa1\u6307\u6a19\u304c\u307e\u305a\u5065\u5eb7\u5bff\u547d\uff08\u767a\u75c7\u9045\u5ef6\u30fb\u6a5f\u80fd\uff09\u306b\u7f6e\u304b\u308c\u308b\u7406\u7531<\/h3>\n

\u8001\u5316\u6a5f\u69cb\u3092\u6a19\u7684\u306b\u3057\u3066\u8907\u6570\u75be\u60a3\u306e\u767a\u75c7\u3092\u9045\u3089\u305b\u308b\u3068\u3044\u3046\u767a\u60f3\u306f geroscience \u3068\u3057\u3066\u6574\u7406\u3055\u308c\u3001\u81e8\u5e8a\u8a66\u9a13\u306e\u8a2d\u8a08\u306b\u3082\u5f71\u97ff\u3057\u3066\u3044\u308b\u3002Barzilai \u3089\u306f TAME \u69cb\u60f3\u3067\u3001\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u3092\u7528\u3044\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3001\u304c\u3093\u3001\u8a8d\u77e5\u75c7\u3001\u6b7b\u4ea1\u306a\u3069\u306e\u8907\u5408\u30a2\u30a6\u30c8\u30ab\u30e0\u3092\u300c\u767a\u75c7\u307e\u3067\u306e\u6642\u9593\u300d\u3068\u3057\u3066\u8a55\u4fa1\u3059\u308b\u67a0\u7d44\u307f\u3092\u63d0\u6848\u3057\u305f[37]<\/a>\u3002\u307e\u305f mTOR \u963b\u5bb3\u304c\u9ad8\u9f62\u8005\u306e\u514d\u75ab\u6a5f\u80fd\u306b\u5f71\u97ff\u3057\u3046\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u8a66\u9a13\u3082\u3042\u308b[38]<\/a>\u3002\u3053\u3053\u3067\u91cd\u8981\u306a\u306e\u306f\u3001\u5c3e\u90e8\u306e\u6700\u5927\u5bff\u547d\u3092\u76f4\u63a5\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u3059\u308b\u9577\u671f\u8a66\u9a13\u306f\u502b\u7406\u30fb\u671f\u9593\u30fb\u526f\u4f5c\u7528\u306e\u89b3\u70b9\u3067\u96e3\u3057\u304f\u3001\u307e\u305a\u5065\u5eb7\u5bff\u547d\u3084\u6a5f\u80fd\u6539\u5584\u3068\u3057\u3066\u8a55\u4fa1\u3055\u308c\u308b\u6bb5\u968e\u306b\u3042\u308b\u3068\u3044\u3046\u70b9\u3067\u3042\u308b\u3002<\/p>\n

\n

8. \u5065\u5eb7\u5bff\u547d\u3092\u6700\u5927\u5316\u3057\u305f\u7d50\u679c\u3001\u6700\u5927\u5bff\u547d\u306f\u300c\u81ea\u7136\u306b\u300d\u3069\u3053\u307e\u3067\u5f15\u304d\u4e0a\u304c\u308b\u304b<\/h2>\n

\u5065\u5eb7\u5bff\u547d\u3092\u6700\u5927\u5316\u3059\u308b\u3068\u300190 \u4ee3\u5f8c\u534a\u304b\u3089 100 \u4ee3\u524d\u534a\u307e\u3067\u81ea\u7acb\u3057\u3066\u5230\u9054\u3059\u308b\u4eba\u53e3\u304c\u5897\u3048\u3001110 \u6b73\u5230\u9054\u8005\uff08supercentenarians\uff09\u3082\u5897\u3048\u308b\u3002\u305d\u306e\u7d50\u679c\u3068\u3057\u3066\u8a18\u9332\u4e0a\u306e\u6700\u9ad8\u9f62\u306f\u78ba\u7387\u7684\u306b\u66f4\u65b0\u3055\u308c\u3084\u3059\u304f\u306a\u308b\u3002\u3057\u304b\u3057\u3001105 \u6b73\u4ee5\u964d\u306e\u6b7b\u4ea1\u7387\u304c\u9ad8\u3044\u307e\u307e\u3067\u3042\u308c\u3070\u3001\u751f\u5b58\u8005\u306f\u5e74\u3054\u3068\u306b\u6025\u6e1b\u8870\u3059\u308b\u305f\u3081\u3001\u8a18\u9332\u304c 10 \u5e74\u5358\u4f4d\u3067\u81ea\u7136\u306b\u4e0a\u65b9\u30b7\u30d5\u30c8\u3059\u308b\u72b6\u6cc1\u306f\u4f5c\u308a\u306b\u304f\u3044\u3002\u3053\u306e\u7d50\u8ad6\u306f\u3001105 \u6b73\u4ee5\u964d\u306e\u6b7b\u4ea1\u30cf\u30b6\u30fc\u30c9\u304c\u9ad8\u3044\u6c34\u6e96\u3067\u63a8\u79fb\u3059\u308b\u3068\u3044\u3046\u5831\u544a\u3068\u6574\u5408\u3059\u308b[31]<\/a>\u3002\u3057\u305f\u304c\u3063\u3066\u5065\u5eb7\u5bff\u547d\u6700\u5927\u5316\u306e\u4e3b\u52b9\u679c\u306f\u300c\u58c1\u305d\u306e\u3082\u306e\u3092\u58ca\u3059\u300d\u3053\u3068\u3067\u306f\u306a\u304f\u3001\u300c\u58c1\u306e\u624b\u524d\u307e\u3067\u5143\u6c17\u306b\u5230\u9054\u3059\u308b\u4eba\u6570\u3092\u5897\u3084\u3059\u300d\u3053\u3068\u3067\u3042\u308b\u3002\u6700\u5927\u5bff\u547d\u3092\u5927\u304d\u304f\u62bc\u3057\u4e0a\u3052\u308b\u306b\u306f\u3001\u5c3e\u90e8\u306e\u6b7b\u4ea1\u7387\u66f2\u7dda\u305d\u306e\u3082\u306e\u3092\u4e0b\u3052\u308b\u4ecb\u5165\u304c\u5fc5\u8981\u306b\u306a\u308b\u3002<\/p>\n

\n

9. \u5065\u5eb7\u5bff\u547d 90 \u6b73\u793e\u4f1a\u306f\u6210\u7acb\u3059\u308b\u306e\u304b\uff1a\u533b\u7642\u30fb\u5e74\u91d1\u30fb\u52b4\u50cd\u30fb\u502b\u7406<\/h2>\n

9.1 \u533b\u7642\uff1a\u6cbb\u7642\u4e2d\u5fc3\u304b\u3089\u4e88\u9632\u30fb\u56de\u5fa9\u30fb\u5728\u5b85\u30fb\u30ea\u30cf\u4e2d\u5fc3\u3078<\/h3>\n

\u5065\u5eb7\u5bff\u547d 90 \u6b73\u793e\u4f1a\u306f\u300c\u533b\u7642\u304c\u8efd\u304f\u306a\u308b\u793e\u4f1a\u300d\u3067\u306f\u306a\u3044\u3002\u3080\u3057\u308d\u533b\u7642\u3068\u4ecb\u8b77\u306e\u5f62\u304c\u5909\u308f\u308b\u793e\u4f1a\u3067\u3042\u308b\u300290 \u6b73\u307e\u3067\u81ea\u7acb\u3067\u304d\u308b\u4eba\u304c\u5897\u3048\u308b\u307b\u3069\u3001\u80ba\u708e\u3001\u9aa8\u6298\u3001\u611f\u67d3\u75c7\u3001\u5fc3\u4e0d\u5168\u5897\u60aa\u3068\u3044\u3063\u305f\u30a4\u30d9\u30f3\u30c8\u304b\u3089\u751f\u6d3b\u3078\u623b\u3059\u9700\u8981\u304c\u5897\u3048\u308b\u3002\u305d\u306e\u305f\u3081\u5728\u5b85\u533b\u7642\u3001\u8a2a\u554f\u770b\u8b77\u3001\u5730\u57df\u30ea\u30cf\u3001\u6804\u990a\u3001\u53e3\u8154\u3001\u793e\u4f1a\u53c2\u52a0\u652f\u63f4\u3068\u3044\u3063\u305f\u56de\u5fa9\u30a4\u30f3\u30d5\u30e9\u304c\u4e2d\u5fc3\u306b\u306a\u308b\u3002\u3053\u3053\u3067\u91cd\u8981\u306a\u6982\u5ff5\u304c\u4e0d\u5065\u5eb7\u671f\u9593\u306e\u5727\u7e2e\uff08compression of morbidity\uff09\u3067\u3042\u308a\u3001Fries \u306f\u6162\u6027\u75be\u60a3\u3084\u969c\u5bb3\u306e\u958b\u59cb\u3092\u9045\u3089\u305b\u3001\u4e0d\u5065\u5eb7\u671f\u9593\u3092\u77ed\u304f\u5727\u7e2e\u3067\u304d\u308b\u53ef\u80fd\u6027\u3092\u8ad6\u3058\u305f[39]<\/a>\u3002\u5727\u7e2e\u306b\u6210\u529f\u3059\u308c\u3070\u5e73\u5747\u5bff\u547d\u304c\u4f38\u3073\u3066\u3082\u533b\u7642\u30fb\u4ecb\u8b77\u306e\u7dcf\u8ca0\u62c5\u306f\u4e00\u5b9a\u7a0b\u5ea6\u6291\u3048\u3089\u308c\u5f97\u308b\u304c\u3001\u5727\u7e2e\u306b\u5931\u6557\u3059\u308c\u3070\u5bff\u547d\u5ef6\u4f38\u304c\u305d\u306e\u307e\u307e\u8ca0\u62c5\u5897\u306b\u306a\u308b\u3002\u65e5\u672c\u306e\u4ecb\u8b77\u4fdd\u967a\u5236\u5ea6\u3068\u9ad8\u9f62\u793e\u4f1a\u653f\u7b56\u306f\u3001\u3053\u306e\u5727\u7e2e\u3092\u793e\u4f1a\u3068\u3057\u3066\u3069\u3046\u5b9f\u73fe\u3059\u308b\u304b\u3068\u3044\u3046\u8ab2\u984c\u3068\u76f4\u7d50\u3059\u308b[40]<\/a>[41]<\/a>\u3002<\/p>\n

9.2 \u5e74\u91d1\uff1a\u53d7\u7d66\u671f\u9593\u306e\u4f38\u9577\u3092\u5c31\u52b4\u53c2\u52a0\u3067\u5438\u53ce\u3067\u304d\u308b\u304b<\/h3>\n

\u5065\u5eb7\u5bff\u547d\u304c\u4f38\u3073\u308b\u3053\u3068\u306f\u300c\u50cd\u3051\u308b\u9ad8\u9f62\u8005\u304c\u5897\u3048\u308b\u300d\u3053\u3068\u3067\u3082\u3042\u308b\u3002\u5c31\u52b4\u304c\u5897\u3048\u306a\u3044\u306e\u306b\u53d7\u7d66\u671f\u9593\u3060\u3051\u304c\u4f38\u3073\u308c\u3070\u73fe\u5f79\u8ca0\u62c5\u304c\u81e8\u754c\u5316\u3059\u308b\u305f\u3081\u3001\u5e74\u91d1\u5236\u5ea6\u306f\u5c31\u52b4\u5ef6\u9577\u3068\u30bb\u30c3\u30c8\u3067\u8a2d\u8a08\u3055\u308c\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002OECD \u306f\u65e5\u672c\u306b\u304a\u3051\u308b\u9ad8\u9f62\u5c31\u52b4\u306e\u5236\u5ea6\u6539\u9769\u3068\u3057\u3066\u3001\u9000\u8077\u6163\u884c\u3001\u8cc3\u91d1\u5236\u5ea6\u3001\u6280\u80fd\u66f4\u65b0\u3001\u52b4\u50cd\u6761\u4ef6\u6539\u5584\u306a\u3069\u3092\u5177\u4f53\u7684\u306b\u8ad6\u3058\u3066\u3044\u308b[42]<\/a>\u3002\u53d7\u7d66\u958b\u59cb\u5e74\u9f62\u306e\u8abf\u6574\u306f\u5358\u72ec\u3067\u62bc\u3057\u4ed8\u3051\u308b\u3068\u4e0d\u516c\u5e73\u611f\u304c\u7206\u767a\u3057\u3084\u3059\u3044\u306e\u3067\u3001\u5065\u5eb7\u683c\u5dee\u5bfe\u7b56\u3001\u4ecb\u8b77\u3068\u5c31\u52b4\u306e\u4e21\u7acb\u652f\u63f4\u3001\u67d4\u8edf\u306a\u50cd\u304d\u65b9\u306e\u6574\u5099\u3068\u4e00\u4f53\u3067\u884c\u3046\u5fc5\u8981\u304c\u3042\u308b\u3002<\/p>\n

9.3 \u52b4\u50cd\uff1a70 \u4ee3\u5c31\u52b4\u3092\u524d\u63d0\u306b\u300c\u4ed5\u4e8b\u306e\u8a2d\u8a08\u300d\u3092\u5909\u3048\u308b<\/h3>\n

\u5065\u5eb7\u5bff\u547d 90 \u6b73\u793e\u4f1a\u306e\u6210\u7acb\u306f\u3001\u533b\u7642\u3088\u308a\u3082\u52b4\u50cd\u5e02\u5834\u8a2d\u8a08\u306b\u4f9d\u5b58\u3059\u308b\u9762\u304c\u5927\u304d\u3044\u3002\u306a\u305c\u306a\u3089\u533b\u7642\u30fb\u4ecb\u8b77\u30fb\u5e74\u91d1\u3092\u652f\u3048\u308b\u306e\u306f\u52b4\u50cd\u4f9b\u7d66\u3067\u3042\u308a\u3001\u8d85\u9ad8\u9f62\u5316\u304c\u9032\u3080\u307b\u3069\u4f9d\u5b58\u6bd4\u7387\u304c\u4e0a\u304c\u308b\u304b\u3089\u3067\u3042\u308b\u3002OECD \u306f\u9ad8\u9f62\u5316\u793e\u4f1a\u3067\u306e\u5c31\u52b4\u53c2\u52a0\u62e1\u5927\u3092\u91cd\u8981\u8ab2\u984c\u3068\u3057\u3066\u6271\u3044\u3001\u5236\u5ea6\u6539\u9769\u306e\u65b9\u5411\u6027\u3092\u793a\u3057\u3066\u3044\u308b[42]<\/a>[43]<\/a>\u3002\u305f\u3060\u3057 70 \u4ee3\u5c31\u52b4\u306f 20 \u4ee3\u306e\u50cd\u304d\u65b9\u306e\u5ef6\u9577\u3067\u306f\u6210\u7acb\u3057\u306a\u3044\u3002\u77ed\u6642\u9593\u3001\u65ad\u7d9a\u5c31\u52b4\u3001\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u5358\u4f4d\u3001\u6559\u80b2\u3001\u54c1\u8cea\u3001\u8abf\u6574\u3001\u76e3\u7763\u3068\u3044\u3063\u305f\u5f79\u5272\u3078\u30b7\u30d5\u30c8\u3057\u3001\u8eab\u4f53\u8ca0\u8377\u3068\u8a8d\u77e5\u8ca0\u8377\u3092\u9069\u5207\u306b\u914d\u5206\u3057\u305f\u8a2d\u8a08\u304c\u5fc5\u8981\u306b\u306a\u308b\u3002\u3053\u308c\u306f\u9ad8\u9f62\u8005\u306e\u305f\u3081\u3060\u3051\u3067\u306a\u304f\u3001\u4ecb\u8b77\u3068\u5c31\u52b4\u306e\u4e21\u7acb\u3067\u75b2\u5f0a\u3057\u3084\u3059\u3044 50 \u301c 60 \u4ee3\u306e\u52b4\u50cd\u7dad\u6301\u306b\u3082\u76f4\u7d50\u3059\u308b\u3002<\/p>\n

9.4 \u502b\u7406\uff1a\u914d\u5206\u30fb\u610f\u601d\u6c7a\u5b9a\u30fb\u683c\u5dee\u3092\u624b\u7d9a\u304d\u3068\u3057\u3066\u5236\u5ea6\u5316\u3059\u308b<\/h3>\n

\u5065\u5eb7\u5bff\u547d\u304c\u4f38\u3073\u308b\u307b\u3069\u502b\u7406\u554f\u984c\u304c\u6d88\u3048\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3002\u5f62\u304c\u5909\u308f\u308b\u3002\u7b2c\u4e00\u306b\u914d\u5206\u306e\u502b\u7406\u304c\u5148\u92ed\u5316\u3059\u308b\u3002\u9ad8\u984d\u533b\u7642\u3001\u65b0\u85ac\u3001\u4ecb\u8b77\u8cc7\u6e90\u3001\u5728\u5b85\u30a4\u30f3\u30d5\u30e9\u3078\u306e\u6295\u8cc7\u3092\u3069\u3046\u914d\u5206\u3059\u308b\u304b\u3002\u7b2c\u4e8c\u306b\u610f\u601d\u6c7a\u5b9a\u306e\u502b\u7406\u3067\u3042\u308b\u3002\u8a8d\u77e5\u75c7\u3084\u610f\u601d\u80fd\u529b\u4f4e\u4e0b\u306e\u5c40\u9762\u3067\u3001\u4e8b\u524d\u6307\u793a\u3084\u4ee3\u7406\u610f\u601d\u6c7a\u5b9a\u306e\u624b\u7d9a\u304d\u3092\u6a19\u6e96\u5316\u3057\u306a\u3044\u3068\u73fe\u5834\u304c\u7834\u7dbb\u3059\u308b\u3002\u7b2c\u4e09\u306b\u683c\u5dee\u306e\u502b\u7406\u3067\u3042\u308b\u3002Lancet Commission \u304c\u6559\u80b2\u3001\u96e3\u8074\u3001\u793e\u4f1a\u7684\u5b64\u7acb\u306a\u3069\u793e\u4f1a\u8981\u56e0\u3092\u30ea\u30b9\u30af\u56e0\u5b50\u3068\u3057\u3066\u542b\u3081\u308b\u306e\u306f\u3001\u5065\u5eb7\u5bff\u547d\u304c\u793e\u4f1a\u7684\u7523\u7269\u3067\u3082\u3042\u308b\u3053\u3068\u3092\u793a\u3059[17]<\/a>\u3002\u307e\u305f\u3001\u75be\u75c5\u8ca0\u8377\u63a8\u8a08\uff08GBD\uff09\u7cfb\u306e\u7814\u7a76\u306f\u3001\u30ea\u30b9\u30af\u56e0\u5b50\u3068\u969c\u5bb3\u8ca0\u8377\u306e\u56fd\u5225\u63a8\u8a08\u3092\u63d0\u4f9b\u3057\u3001\u653f\u7b56\u304c\u3069\u3053\u306b\u52b9\u304f\u304b\u3092\u5b9a\u91cf\u7684\u306b\u53ef\u8996\u5316\u3059\u308b\u5165\u53e3\u306b\u306a\u308b[44]<\/a>\u3002<\/p>\n

\n

10. 2100 \u5e74\u306b\u5411\u3051\u3066\u300c\u4f55\u3092\u3059\u308c\u3070\u4f55\u304c\u52d5\u304f\u304b\u300d\uff1a\u6307\u6a19\u5225\u306e\u30ec\u30d0\u30fc\u3092\u6574\u7406\u3059\u308b<\/h2>\n

10.1 \u5e73\u5747\u5bff\u547d\u3092\u52d5\u304b\u3059\u30ec\u30d0\u30fc<\/h3>\n

\u5e73\u5747\u5bff\u547d\u306f\u3001\u6b7b\u4ea1\u7387\u304c\u9ad8\u3044\u5e74\u9f62\u5e2f\u306e\u6539\u5584\u3067\u5927\u304d\u304f\u52d5\u304f\u3002\u65e5\u672c\u3067\u306f\u65e2\u306b\u4e73\u5e7c\u5150\u6b7b\u4ea1\u3084\u611f\u67d3\u75c7\u6b7b\u4ea1\u304c\u4f4e\u6c34\u6e96\u3067\u3042\u308b\u305f\u3081\u3001\u4eca\u5f8c\u306e\u4f38\u3073\u306f\u6162\u6027\u75be\u60a3\u306e\u4e00\u6b21\u4e88\u9632\u3068\u9ad8\u9f62\u671f\u306e\u91cd\u75c7\u5316\u56de\u907f\u306b\u4f9d\u5b58\u3059\u308b\u3002\u305d\u306e\u610f\u5473\u3067\u3001\u5e73\u5747\u5bff\u547d\u306f\u4f38\u3073\u308b\u3068\u3057\u3066\u3082\u4f38\u3073\u65b9\u306f\u9013\u6e1b\u3057\u3084\u3059\u3044\u3002<\/p>\n

10.2 \u5065\u5eb7\u5bff\u547d\u3092\u52d5\u304b\u3059\u30ec\u30d0\u30fc<\/h3>\n

\u5065\u5eb7\u5bff\u547d\u306f\u3001\u751f\u6d3b\u6a5f\u80fd\u4f4e\u4e0b\u306e\u5165\u53e3\u3092\u9045\u3089\u305b\u308b\u4ecb\u5165\u3067\u52d5\u304f\u3002\u30d5\u30ec\u30a4\u30eb\u5bfe\u7b56\uff08\u7b4b\u529b\u3001\u6804\u990a\u3001\u8ee2\u5012\u4e88\u9632\uff09\u3001\u8840\u7ba1\u30ea\u30b9\u30af\u7ba1\u7406\u3001\u611f\u899a\u969c\u5bb3\u3078\u306e\u5bfe\u5fdc\u3001\u793e\u4f1a\u53c2\u52a0\u306e\u7dad\u6301\u304c\u76f8\u4e92\u306b\u88dc\u5b8c\u3057\u5408\u3046\u3002WHO \u306e\u8eab\u4f53\u6d3b\u52d5\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306f\u4ecb\u5165\u306e\u6700\u4f4e\u30e9\u30a4\u30f3\u3092\u4e0e\u3048\u308b[24]<\/a>\u3002\u8a8d\u77e5\u75c7\u4e00\u6b21\u4e88\u9632\u306f\u4e2d\u5e74\u671f\u304b\u3089\u306e\u9577\u671f\u6226\u3067\u3042\u308a\u3001Lancet Commission \u3068 WHO \u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u304c\u5177\u4f53\u7684\u306a\u56e0\u5b50\u3092\u63d0\u793a\u3057\u3066\u3044\u308b[17]<\/a>[19]<\/a>\u3002<\/p>\n

10.3 \u6700\u5927\u5bff\u547d\u3092\u52d5\u304b\u3059\u30ec\u30d0\u30fc<\/h3>\n

\u6700\u5927\u5bff\u547d\u3092\u5927\u304d\u304f\u52d5\u304b\u3059\u306b\u306f\u3001\u5c3e\u90e8\u306e\u6b7b\u4ea1\u7387\u66f2\u7dda\u305d\u306e\u3082\u306e\u3092\u4e0b\u3052\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002\u8001\u5316\u304c\u591a\u56e0\u5b50\u3067\u3042\u308b\u4ee5\u4e0a\u3001\u5358\u4e00\u4ecb\u5165\u3067\u306f\u4ee3\u66ff\u7d4c\u8def\u304c\u6b8b\u308a\u3084\u3059\u3044\u3002\u8001\u5316\u7d30\u80de\u3001\u6162\u6027\u708e\u75c7\u3001\u514d\u75ab\u8001\u5316\u3001CHIP\u3001\u518d\u751f\u4f59\u529b\u306a\u3069\u306e\u540c\u6642\u6700\u9069\u5316\u304c\u5fc5\u8981\u306b\u306a\u308b\u304c\u3001\u9577\u671f\u5b89\u5168\u6027\u3068\u526f\u4f5c\u7528\u306e\u58c1\u304c\u91cd\u3044\u3002\u73fe\u6642\u70b9\u3067\u306f\u3001\u6700\u5927\u5bff\u547d\u3092\u6c7a\u5b9a\u7684\u306b\u62bc\u3057\u4e0a\u3052\u305f\u4eba\u9593\u30c7\u30fc\u30bf\u306f\u78ba\u7acb\u3057\u3066\u304a\u3089\u305a\u3001\u7814\u7a76\u306f\u4e3b\u306b\u5065\u5eb7\u5bff\u547d\u306e\u6539\u5584\u3068\u3057\u3066\u8a55\u4fa1\u3055\u308c\u308b\u6bb5\u968e\u306b\u3042\u308b[37]<\/a>[38]<\/a>\u3002<\/p>\n

\n

11. \u307e\u3068\u3081\uff1a2100 \u5e74\u306e\u5230\u9054\u70b9\u3068\u3001\u6210\u7acb\u6761\u4ef6<\/h2>\n

\u672c\u7a3f\u306e\u7d50\u8ad6\u3092\u6700\u5f8c\u306b\u6574\u7406\u3059\u308b\u3002\u65e5\u672c\u306e\u5065\u5eb7\u5bff\u547d\u306f 2022 \u5e74\u6642\u70b9\u3067\u7537\u6027 72.57 \u5e74\u3001\u5973\u6027 75.45 \u5e74\u3067\u3042\u308a\u3001\u5e73\u5747\u5bff\u547d\u3068\u306e\u5dee\u306f\u5927\u304d\u3044[2]<\/a>[3]<\/a>\u30022100 \u5e74\u306b\u5411\u3051\u3066\u5e73\u5747\u5bff\u547d\u306f 90 \u301c 100 \u6b73\u4ed8\u8fd1\u307e\u3067\u4e0a\u6607\u3057\u5f97\u308b\u304c\u3001\u4f38\u3073\u65b9\u306f\u9013\u6e1b\u3057\u3084\u3059\u3044[9]<\/a>\u3002\u5065\u5eb7\u5bff\u547d\u306f\u30d5\u30ec\u30a4\u30eb\u9023\u9396\u3068\u8a8d\u77e5\u75c7\u4e00\u6b21\u4e88\u9632\u306e\u793e\u4f1a\u5b9f\u88c5\u306b\u3088\u3063\u3066 80 \u4ee3\u5f8c\u534a\u304b\u3089 90 \u6b73\u8fd1\u508d\u307e\u3067\u5230\u9054\u3057\u5f97\u308b\u304c\u3001\u305d\u306e\u6210\u5426\u306f\u533b\u7642\u306e\u56de\u5fa9\u30a4\u30f3\u30d5\u30e9\u5316\u3001\u5e74\u91d1\u3068\u5c31\u52b4\u5236\u5ea6\u306e\u540c\u6642\u6539\u9769\u3001\u52b4\u50cd\u5e02\u5834\u306e\u518d\u8a2d\u8a08\u3001\u914d\u5206\u3068\u610f\u601d\u6c7a\u5b9a\u3068\u683c\u5dee\u306e\u624b\u7d9a\u304d\u5316\u306b\u4f9d\u5b58\u3059\u308b[39]<\/a>[42]<\/a>[17]<\/a>\u3002\u6700\u5927\u5bff\u547d\u306f\u5065\u5eb7\u5bff\u547d\u306e\u5ef6\u4f38\u3067\u8a18\u9332\u66f4\u65b0\u304c\u8d77\u304d\u3084\u3059\u304f\u306a\u308b\u4e00\u65b9\u3001\u5c3e\u90e8\u306e\u6b7b\u4ea1\u7387\u66f2\u7dda\u304c\u786c\u3044\u305f\u3081\u81ea\u7136\u306b 10 \u5e74\u5358\u4f4d\u3067\u4e0a\u65b9\u30b7\u30d5\u30c8\u3059\u308b\u72b6\u6cc1\u306f\u4f5c\u308a\u306b\u304f\u3044[31]<\/a>\u3002\u3057\u305f\u304c\u3063\u3066 2100 \u5e74\u306e\u4eba\u9593\u5bff\u547d\u306e\u5b9f\u50cf\u306f\u3001\u6700\u5927\u5bff\u547d\u306e\u5287\u7684\u4e0a\u9650\u7a81\u7834\u3088\u308a\u5148\u306b\u3001\u5065\u5eb7\u5bff\u547d\u306e\u62e1\u5f35\u3068\u793e\u4f1a\u5236\u5ea6\u306e\u518d\u8a2d\u8a08\u3068\u3057\u3066\u73fe\u308c\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3002<\/p>\n

\n

\u53c2\u8003\u6587\u732e<\/h2>\n
    \n
  1. CDC \/ NCHS overview: U.S. life tables methods (as a general life-table reference) https:\/\/www.cdc.gov\/nchs\/products\/life_tables.htm<\/a><\/li>\n
  2. e-\u30d8\u30eb\u30b9\u30cd\u30c3\u30c8\uff08\u539a\u751f\u52b4\u50cd\u7701\uff09\u300c\u5e73\u5747\u5bff\u547d\u3068\u5065\u5eb7\u5bff\u547d\u300d https:\/\/kennet.mhlw.go.jp\/information\/information\/hale\/h-01-002.html<\/a><\/li>\n
  3. \u539a\u751f\u52b4\u50cd\u7701\u300c\u5065\u5eb7\u5bff\u547d\u306e\u4ee4\u548c 4 \u5e74\u5024\u306b\u3064\u3044\u3066\u300d\uff08PDF\uff09 https:\/\/www.mhlw.go.jp\/content\/10904750\/001363069.pdf<\/a><\/li>\n
  4. WHO Data: Japan\uff08\u5065\u5eb7\u95a2\u9023\u6307\u6a19\u3092\u542b\u3080\u56fd\u5225\u30da\u30fc\u30b8\uff09 https:\/\/data.who.int\/countries\/392<\/a><\/li>\n
  5. WHO Data: HALE dashboard https:\/\/data.who.int\/dashboards\/global-progress\/hale<\/a><\/li>\n
  6. Human Mortality Database (HMD) Overview https:\/\/www.mortality.org\/Project\/Overview<\/a><\/li>\n
  7. International Database on Longevity (IDL) \/ Supercentenarians.org https:\/\/www.supercentenarians.org\/en\/<\/a><\/li>\n
  8. Robine J-M., Allard M., Jeanne Calment validation (MPIDR) https:\/\/www.demogr.mpg.de\/books\/odense\/6\/09.htm<\/a><\/li>\n
  9. Oeppen J., Vaupel JW., \u201cBroken Limits to Life Expectancy\u201d (Science, 2002)\uff08PDF\uff09 https:\/\/user.demogr.mpg.de\/jwv\/pdf\/sciencemay2002.pdf<\/a><\/li>\n
  10. Fried LP. et al., \u201cFrailty in older adults: evidence for a phenotype\u201d (J Gerontol A, 2001) PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/11253156\/<\/a><\/li>\n
  11. Cesari M. et al., frailty concept review (Clin Geriatr Med, 2014) PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/25453345\/<\/a><\/li>\n
  12. WHO fact sheet: Falls https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/falls<\/a><\/li>\n
  13. Cruz-Jentoft AJ. et al., \u201cSarcopenia: revised European consensus on definition and diagnosis (EWGSOP2)\u201d (Age Ageing, 2019) PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/30312372\/<\/a><\/li>\n
  14. Deutz NEP. et al., \u201cProtein intake and exercise for optimal muscle function with aging\u201d (Clin Nutr, 2014) PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/24355036\/<\/a><\/li>\n
  15. Lin FR. et al., hearing loss and incident dementia cohort (JAMA Intern Med, 2013) PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/23337978\/<\/a><\/li>\n
  16. Holt-Lunstad J. et al., social relationships and mortality meta-analysis (PLoS Med, 2010) PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/20668659\/<\/a><\/li>\n
  17. Livingston G. et al., \u201cDementia prevention, intervention, and care: 2024 report of the Lancet Commission\u201d (The Lancet, 2024) abstract https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736%2824%2901296-0\/abstract<\/a><\/li>\n
  18. The Lancet Commission portal: dementia prevention, intervention, and care https:\/\/www.thelancet.com\/commissions-do\/dementia-prevention-intervention-and-care<\/a><\/li>\n
  19. WHO\u300cRisk reduction of cognitive decline and dementia: WHO guidelines\u300d(2019) https:\/\/www.who.int\/publications-detail-redirect\/risk-reduction-of-cognitive-decline-and-dementia<\/a><\/li>\n
  20. NCBI Bookshelf: WHO dementia risk reduction guideline https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK542796\/<\/a><\/li>\n
  21. Ngandu T. et al., \u201cA 2 year multidomain intervention\u2026 (FINGER)\u201d (Lancet, 2015) abstract https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(15)60461-5\/abstract<\/a><\/li>\n
  22. Williamson JD. et al., \u201cEffect of Intensive vs Standard Blood Pressure Control on Dementia\u201d (JAMA, 2019) SPRINT MIND https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2723256<\/a><\/li>\n
  23. SPRINT Research Group, intensive vs standard BP control (NEJM, 2015) abstract https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1511939<\/a><\/li>\n
  24. WHO guidelines on physical activity and sedentary behaviour (2020) https:\/\/www.who.int\/publications\/i\/item\/9789240015128<\/a><\/li>\n
  25. Bolland MJ. et al., vitamin D supplementation and falls\/fractures meta-analysis (BMJ, 2014) PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/25190675\/<\/a><\/li>\n
  26. L\u00f3pez-Ot\u00edn C. et al., \u201cThe Hallmarks of Aging\u201d (Cell, 2013) PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/23746838\/<\/a><\/li>\n
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  40. \u5185\u95a3\u5e9c\u300c\u9ad8\u9f62\u793e\u4f1a\u767d\u66f8\u300d\uff08\u5e74\u6b21\u7248\u30c8\u30c3\u30d7\uff09 https:\/\/www8.cao.go.jp\/kourei\/whitepaper\/index-w.html<\/a><\/li>\n
  41. \u539a\u751f\u52b4\u50cd\u7701 \u4ecb\u8b77\u4fdd\u967a\u5236\u5ea6\u306e\u6982\u8981\uff08\u7dcf\u5408\u30da\u30fc\u30b8\uff09 https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/hukushi_kaigo\/kaigo_koureisha\/index.html<\/a><\/li>\n
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  44. IHME \/ GBD Results tool\uff08\u75be\u75c5\u8ca0\u8377\u30fb\u30ea\u30b9\u30af\u56e0\u5b50\u306e\u56fd\u5225\u63a8\u8a08\uff09 https:\/\/ghdx.healthdata.org\/gbd-results-tool<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    \u65e5\u672c\u7d4c\u6e08\u65b0\u805e\u306b 2100 \u5e74\u306e\u5bff\u547d\u304c\u73fe\u5728\u3088\u308a\u4f38\u3073\u308b\u3053\u3068\u3092\u524d\u63d0\u3068\u3057\u305f\u8a18\u4e8b\u304c\u63b2\u8f09\u3055\u308c\u3066\u3044\u305f\u3002\u305d\u3053\u3067\u672c\u7a3f\u3067\u306f\u30012100 \u5e74\u306b\u4eba\u9593\u306e\u5bff\u547d\u304c\u3069\u3053\u307e\u3067\u5230\u9054\u3057\u3046\u308b\u306e\u304b\u3092\u3001\u5e73\u5747\u5bff\u547d\u3001\u5065\u5eb7\u5bff\u547d\u3001\u6700\u5927\u5bff\u547d\u3068\u3044\u3046 3 \u3064\u306e\u6307\u6a19\u3092\u53b3\u5bc6\u306b\u533a\u5225\u3057\u306a … \u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-3280","post","type-post","status-publish","format-standard","hentry","category-society"],"_links":{"self":[{"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/posts\/3280","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/comments?post=3280"}],"version-history":[{"count":5,"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/posts\/3280\/revisions"}],"predecessor-version":[{"id":4190,"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/posts\/3280\/revisions\/4190"}],"wp:attachment":[{"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/media?parent=3280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/categories?post=3280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.id774.net\/entry\/wp-json\/wp\/v2\/tags?post=3280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}